ceesdekker.net - An Overview
ceesdekker.net - An Overview
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Rotary motion of DNA rotors on nanopores. Top rated row: Uncooked online video from the Cy5 channel of each rotor. Middle row: corresponding one-particle localization final results of both of those ends with the DNA rotors. The place of the present frame is marked as orange and blue dots, and also the trajectory of The ten frames ahead of the current frame is shown as solid traces.
1996, initially mesoscopic charge density waves units; and to start with electrical measurements on just one steel nanocluster concerning nanoelectrodes
‘It absolutely was simply a make any difference of selecting up a guide on mobile biology and beginning to go through. I'd come from a environment of extremely-higher vacuums, cryostats and quantum phenomena, and now I had been Performing at area temperature with molecular biology kits.
Non-equilibrium folding of personal DNA molecules recaptured approximately one thousand instances in a very stable condition nanopore
2010, designed a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by way of graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into stable-point out nanopores
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en met 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic structures to ceesdekker.net sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement with the molecular and cellular degree. Our tasks include things like the subsequent:
2000, discovery that nanotubes can have extraordinary huge present-day densities; settled the controversial situation of Digital transport by way of DNA molecules by measurements of insulating actions at the single molecule degree; and demonstration of the AFM system for single-molecule manipulation of nanotubes
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‘The fantastically refined way through which factors in nature operate in no way ceases to amaze me. If we remedy the puzzle of how lifestyle arrived into staying, I assume that my amazement on the complexity of development can have elevated and with it my awe with the greatness on the Creator.’
Tests pseudotopological and nontopological designs for SMC-pushed DNA loop extrusion versus roadblock-traversal experiments
1999, 1st measurement from the wavefunction of solitary molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for the new Luttinger description of interacting electrons in nanotubes
2005, discovery with the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of very long-variety conformational improvements in Mre11/DNA restore complexes; and to start with force measurements over a DNA molecule in a nanopore
Last but not least, I'll briefly sketch several of our Thoughts to discover the creating of synthetic cells, exclusively our initially techniques to determine artificial mobile division.